Source-linked briefing Science

Motherhood Tunes Hypothalamic Stress Circuits, Study Finds

Motherhood Tunes Hypothalamic Stress Circuits, Study Finds

A Nature study using fiber photometry in mice shows that while CRH neuron responses to external stressors are not broadly suppressed during lactation, hormone output is reduced and responses to pup cues are amplified. The findings reveal targeted adaptations that may promote maternal behaviors and offspring survival.

Original headline

Adaptation of hypothalamic CRH neuron responses to stress and pup cues during motherhood