Source-linked briefing Science

Scientists Identify TWIK-1 as Dual Regulator of Touch and Chronic Pain

Scientists Identify TWIK-1 as Dual Regulator of Touch and Chronic Pain

Researchers reported that the TWIK-1 potassium channel in spinal and peripheral sensory neurons acts as a molecular switch managing touch responses and persistent neuropathic pain. The findings, published in Signal Transduction and Targeted Therapy, point to a potential therapeutic target.

Original headline

Researchers discover molecular 'switch' that simultaneously manages touch and pain