Source-linked briefing Science

Study identifies IGF2 as key signal guiding human kidney development

Study identifies IGF2 as key signal guiding human kidney development

Penn Medicine researchers report that developing human kidney cells are directed by soluble cues from neighboring cells, with IGF2 sustaining stem-like populations. The findings derive rules directly from human tissue rather than animal models.

Original headline

Soluble signals released by neighboring cells direct how the human kidney is built