Source-linked briefing Science

Compact TIGRa Platform Enhances In Vivo Gene Activation Delivery

Compact TIGRa Platform Enhances In Vivo Gene Activation Delivery

TIGRa, a gene activation platform about half the size of CRISPRa, is reported to markedly improve therapeutic deliverability in vivo. The smaller footprint could ease vector packaging constraints and broaden gene activation applications.

Original headline

Smaller Gene Activation Platform TIGRa Improves In Vivo Deliverability